Drug Review Package. 10903 New Hampshire Avenue Silver Spring, MD 20993 Ph. 1-888-INFO-FDA (1-888-463-6332) Contact FDATri-Luma Cream is used for Lightens light brown color patches on skin, Age spots, Skin discolorations associated with pregnancy, Rough patches and tiny bumps on skin, Skin trauma, and other conditions. Tri-Luma Cream may also be used for purposes not listed in this medication guide. Tri-Luma Cream contains Fluocinolone Acetonide.Tri-Luma is a combination medication used to treat melasma (dark skin patches) on the face. While it only needs to be applied once a day, side effects, like skin redness and burning, are common. Reviewed by: Sean Moshrefi, PharmD. Christina Aungst, PharmD. Last reviewed on January 28, 2021.Tri-Luma Coupons, Prices, and Savings Card. This combination medication is used to treat melasma on the face. Learn more about fluocinolone-hydroquinone-tretinoin topical . 1 . This is a brand name drug and a generic may be available. The average cost for 1 Tube Of Cream, 30gm of 0.01-4-0.05% each, is $278.99.TRI-LUMA Cream is a combination of fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) that is indicated for the short-term treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens. 1. 7. 7 comments. C_Chrono • 3 yr. ago. I started tretinoin first. It helped with acne scars but did not help with sun spots. So after more than a year of almost daily use without buffering, I opted for Tri-Luma. I followed the instructions faithfully and used it for 8 weeks only. I was already using 0.05 tretinoin for months so the ... Jun 1, 2008 · I was on tri-luma for lightening dark inconsistencies on my skin (not freckles or sunspots, mine are darker). But I'm not insured so I dont feel like spending 250.00 just to get a prescription for then a 125.00 little 30mg tube of lightening cream (why is everything sooo expensive). Are there any over the counter alternatives...The summer is ... Tri-Luma Cream Authenticity. Tests conducted by the FDA conclude that TRI-LUMA Cream is more effective than most other similar products. Patients with melasma were benchmarked and examined for melasma severity right at the beginning of the test and after the marker weeks of 1, 2, 4, and 8 of Tri-Luma Cream treatment. Test results were evaluated ...Hydroquinone, tretinoin, and topical corticosteroids are well established monotherapeutic agents for treating melasma and hyperpigmentation; however, a stable, once-daily formulation triple combination cream containing 0.05% tretinoin, 4.0% hydroquinone, and 0.01% fluocinolone acetonide (Tri-Luma) represents the only commercially available ... Jan 18, 2002 · A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma. Patent expiration dates: September 8, 2023. . Tri Luma has definitely worked for me. I first got acne about 5 years ago and did the whole acutane thing, it cleared my skin, and i was clear for about 3 years (with of course red marks and... This element serves to reduce the pigmentation of the blemishes. It inhibits the production of melanin, lightening the skin. Fluocinolone acetonide 0.01%. The third key ingredient. This is a corticosteroid, added to the compound to reduce inflammation caused by the condition. Patients using Tri-Luma are encouraged to limit their exposure to the ...May 13, 2020 · User Reviews for Tri-Luma to treat Melasma (Page 2) Tri-Luma has an average rating of 7.5 out of 10 from a total of 85 reviews for the treatment of Melasma. 71% of reviewers reported a positive experience, while 22% reported a negative experience. Tri-Luma is a cream that is prescribed by a doctor or dermatologist to treat melasma. This cream contains a combination of ingredients that help heal skin and clear dark spots. These ingredients include hydroquinone, tretinoin, and fluocinolone acetonide. Hydroquinone is a skin lightener that works by bleaching the skin.Tri-Luma® Cream is a unique triple-combination topical therapy that is used for the short-term treatment of dark spots that are associated with moderate to severe facial melasma. Fluocinolone acetonide 0.01% is a mild corticosteroid that helps to reduce inflammation.Tri-Luma Coupons, Prices, and Savings Card. This combination medication is used to treat melasma on the face. Learn more about fluocinolone-hydroquinone-tretinoin topical . 1 . This is a brand name drug and a generic may be available. The average cost for 1 Tube Of Cream, 30gm of 0.01-4-0.05% each, is $278.99. A dermatologist stated (see link) that "you'll know Tri-luma expired when it changes the color". New Triluma is light yellow. To WHAT does the color change TO when the product expires? For example, my Tri-luma is 4 years past expiry date and the color is still as if bought yesterday (light yellow). Given, I've stored it in the fridge or away ...Triluma Cream 15gm Description. Tri Luma Cream contains a combination of Fluocinolone, Hydroquinone and Tretinoin. It is used in adults to treat melasma of the face (dark and discoloured patches on the skin). Do not use this medici. Tri Luma has definitely worked for me. I first got acne about 5 years ago and did the whole acutane thing, it cleared my skin, and i was clear for about 3 years (with of course red marks and... Tri Luma Crema 15 g. $970.00. En Stock. SKU. 3499320002448 * Precio exclusivo de tienda en línea. * Producto sujeto a disponibilidad. * Descuento ya incluído en ...Tri-Luma. *Costco Member Prescription Program pricing is subject to change without notice and may vary by location. Contact the local pharmacy listed for current discount program card prices or for any medications or quantities not displayed above. Powered by Costco Health Solutions. Charitable Contributions. Which patents cover Tri-luma, and when can generic versions of Tri-luma launch? Tri-luma is a drug marketed by Galderma Labs Lp and is included in one NDA. There are two patents protecting this drug. This drug has twenty-nine patent family members in eighteen countries. The generic ingredient in TRI-LUMA is fluocinolone acetonide; hydroquinone ...This element serves to reduce the pigmentation of the blemishes. It inhibits the production of melanin, lightening the skin. Fluocinolone acetonide 0.01%. The third key ingredient. This is a corticosteroid, added to the compound to reduce inflammation caused by the condition. Patients using Tri-Luma are encouraged to limit their exposure to the ...Hydroquinone, tretinoin, and topical corticosteroids are well established monotherapeutic agents for treating melasma and hyperpigmentation; however, a stable, once-daily formulation triple combination cream containing 0.05% tretinoin, 4.0% hydroquinone, and 0.01% fluocinolone acetonide (Tri-Luma) represents the only commercially available ...See full list on drugs.com View all Tri-Luma prices. Get free Discount Card. Get free Discount Card. Dosage Form(s) Available: N/A. Topical cream; Brand Names: Tri-Luma, Triderma: Other fluocinolone / hydroquinone / tretinoin brands include: Triderma: Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original ...Aug 31, 2023 · Which patents cover Tri-luma, and when can generic versions of Tri-luma launch? Tri-luma is a drug marketed by Galderma Labs Lp and is included in one NDA. There are two patents protecting this drug. This drug has twenty-nine patent family members in eighteen countries. The generic ingredient in TRI-LUMA is fluocinolone acetonide; hydroquinone ... Compare prices and print coupons for Tri-Luma (Fluocinolone, Hydroquinone, and Tretinoin) and other drugs at CVS, Walgreens, and other pharmacies. Prices start at $216.43Para el melasma. La crema Tri-luma contiene hidroquinona, una sustancia despigmentante que bloquea la síntesis de melanina, causando la despigmentación de la piel en el tratamiento del melasma. Se indica para el tratamiento del melasma moderado y severo en el rostro en conjunto con protectores solares y medidas estrictas sobre evitar el sol.User Reviews for Tri-Luma to treat Melasma (Page 2) Tri-Luma has an average rating of 7.5 out of 10 from a total of 85 reviews for the treatment of Melasma. 71% of reviewers reported a positive experience, while 22% reported a negative experience. Reviews for Tri-LumaTri-Luma® Cream is a unique, high-quality topical treatment designed to combat skin hyperpigmentation. This triple-combination therapy is specifically formulated to address conditions such as melasma, dark spots, freckles, and other dark discolorations on the skin. The cream works by lightening the skin, reducing inflammation, and increasing ...Stop using Tri-Luma ® Cream (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) and contact your doctor if you experience: Severe or continued irritation, blistering, oozing, scaling, or crusting. Severe burning or swelling of your skin. Irritation of your eyes, nose, or mouth. Any type of breathing problem.TRI-LUMA MR debe aplicarse una vez al día por la noche, por lo menos 30 minutos antes de acostarse. Lave el rostro y el cuello con un dermolimpiador suave. Enjuague abundantemente y seque la piel. Aplique una delgada película del producto en las áreas hiperpigmentadas incluyendo aproximadamente ½ cm de piel normal alrededor de cada lesión. Triluma Cream (15gm) £ 14.16. Add to your Medicine Cart. Triluma 15 gm Cream Generic Name : Hydroquinon 4%, Tretinoin 0.05%, Fluocinolone 0.01% Topical Cream Generic for : Triluma Manufactured By : Encube Ethicals (Galderma) 1 Cream. Share:Only tri-luma has worked to improve the appearance of this unsightly skin condition. My friends immediately noticed when I used it. Although it is expensive and requires a prescription, I can say it is an excellent product and will definitely improve the appearance of hyperpigmentation, sun spots, freckles or melasma.1. 7. 7 comments. C_Chrono • 3 yr. ago. I started tretinoin first. It helped with acne scars but did not help with sun spots. So after more than a year of almost daily use without buffering, I opted for Tri-Luma. I followed the instructions faithfully and used it for 8 weeks only. I was already using 0.05 tretinoin for months so the ... Tri-luma Cream. Tri-luma Cream is widely recommended for the treatment melasma, a skin condition in which brown and dark patches appear on the face. This effective topical therapy is being used for the treatment of moderate-to-severe dark spots that become facial melasma. Tri-Luma ® cream is designed for topical treatment of dark spots, which are associated with melasma; This is a combination of three complementary active agents: depigmenting agent (4% hydroquinone) – blocks the melanin, and evens skin tone; derivatives of vitamin A (tretinoin 0.05%) – renews and protects the skin; Tri-Luma User Reviews & Ratings (Page 2) Tri-Luma has an average rating of 7.5 out of 10 from a total of 88 reviews on Drugs.com. 71% of reviewers reported a positive experience, while 22% reported a negative experience. Reviews for Tri-LumaMay 13, 2020 · User Reviews for Tri-Luma to treat Melasma (Page 2) Tri-Luma has an average rating of 7.5 out of 10 from a total of 85 reviews for the treatment of Melasma. 71% of reviewers reported a positive experience, while 22% reported a negative experience. It works by decreasing the amount of melanin, a pigment your body makes that gives your skin color. This reduces the appearance of dark spots. Sun prevention measures, including sunscreen, are often combined with this medication. It is a combination of a topical steroid, a skin-lightening agent, and a retinoid. Find patient medical information for Tri-Luma topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.Tri Luma Crema 15 g. $970.00. En Stock. SKU. 3499320002448 * Precio exclusivo de tienda en línea. * Producto sujeto a disponibilidad. * Descuento ya incluído en ... TRI-LUMA Cream is a combination of fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) that is indicated for the short-term treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens.Dec 14, 2022 · TRI-LUMA Cream is a combination of fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) that is indicated for the short-term treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens. Feb 16, 2020 · After stopping Tri-Luma, some of the color change may come back. Some weather conditions may irritate the skin. Talk with the doctor. Use of other skin products while using Tri-Luma may cause more irritation. Talk with your doctor before you use other drugs or products on your skin. Practice good skin care and avoid the sun. TRI-LUMA Cream is a combination of fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) that is indicated for the short-term treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens.Melasma Treatment for Face Cream - Dark Spot Remover Centella Asiatica - Korean Skin Care Beauty Products 40ml/1.35 fl.oz. 139. 700+ bought in past month. $1490 ($11.04/Fl Oz) Save more with Subscribe & Save. FREE delivery Wed, Sep 6 on $25 of items shipped by Amazon. Or fastest delivery Thu, Aug 31.Feb 16, 2020 · After stopping Tri-Luma, some of the color change may come back. Some weather conditions may irritate the skin. Talk with the doctor. Use of other skin products while using Tri-Luma may cause more irritation. Talk with your doctor before you use other drugs or products on your skin. Practice good skin care and avoid the sun. Hydroquinone, tretinoin, and topical corticosteroids are well established monotherapeutic agents for treating melasma and hyperpigmentation; however, a stable, once-daily formulation triple combination cream containing 0.05% tretinoin, 4.0% hydroquinone, and 0.01% fluocinolone acetonide (Tri-Luma) represents the only commercially available ... Some dosage forms listed on this page may not apply to the brand name Tri-Luma. Summary. Common side effects of Tri-Luma include: burning sensation, desquamation, pruritus, erythema of skin, and xeroderma. Continue reading for a comprehensive list of adverse effects.TRI-Luma News. Below are TRI-Luma reviews, ratings, comments submitted by patients and caregivers. Based on a total of 14 ratings/reviews, TRI-Luma has an overall score of 4.86. The effectiveness score is 5 and the side effect score is 6. The scores are on ten point scale: 10 - best, 1 - worst. This information is not vetted and should not be ...May 10, 2022 · Tri-Luma is a prescription product approved for the short-term treatment of dark spots associated with moderate-to-severe melasma of the face. Tri-Luma should only be used under the supervision of ... Save money on Tri-Luma with your free Tri-Luma coupon. Save on Tri-Luma at your local pharmacy! Use your ScriptSave WellRx prescription discount card for savings on all of your prescription medications at pharmacies across the U.S.Jul 12, 2016 · Answer: Tri Luma Usage Making Melasma Darker. If TriLuma is making your skn darker and more sensitive, use a gentler product like Melarase (see below).Daily good habits with topicals may well help you chieve your goals with a good skin system like the Brightening Kit from KareSkin (see link). You may want to start with Melarase and Pigmentation ... Tri luma cream is a prescription-based combination formulation for treating face melasma. The medicinal property of Triluma prevents skin redness, itchiness and swelling. Melasma commonly appears as a dark, patchy spot on the skin (especially on the forehead, cheeks, and chin area).• TRI-LUMA Cream, a combination drug product containing corticosteroid, retinoid, and bleaching agent, is NOT indicated for the maintenance treatment of melasma. After achieving control with TRI-LUMA Cream, some patients may be managed with other treatments instead of triple therapy with TRI-LUMA Cream.See full list on drugs.com May 10, 2022 · Tri-Luma is a prescription product approved for the short-term treatment of dark spots associated with moderate-to-severe melasma of the face. Tri-Luma should only be used under the supervision of ... Tri luma cream is a prescription-based combination formulation for treating face melasma. The medicinal property of Triluma prevents skin redness, itchiness and swelling. Melasma commonly appears as a dark, patchy spot on the skin (especially on the forehead, cheeks, and chin area).Aug 31, 2023 · Which patents cover Tri-luma, and when can generic versions of Tri-luma launch? Tri-luma is a drug marketed by Galderma Labs Lp and is included in one NDA. There are two patents protecting this drug. This drug has twenty-nine patent family members in eighteen countries. The generic ingredient in TRI-LUMA is fluocinolone acetonide; hydroquinone ... Tri-Luma Coupons, Prices, and Savings Card. This combination medication is used to treat melasma on the face. Learn more about fluocinolone-hydroquinone-tretinoin topical . 1 . This is a brand name drug and a generic may be available. The average cost for 1 Tube Of Cream, 30gm of 0.01-4-0.05% each, is $278.99.Save money on Tri-Luma with your free Tri-Luma coupon. Save on Tri-Luma at your local pharmacy! Use your ScriptSave WellRx prescription discount card for savings on all of your prescription medications at pharmacies across the U.S.Answer: 24-48 hours ilnot a problem. No problem with this. Main stability of the actives are protected from UV light, so all good. Melasma is a very common cause of skin pigmentation. It can not be completely cured, however effective treatment are possible. This is because your skin is extremely sensitive to UV and even the smallest amount can ...Tri-Luma Galderma CareConnect Patient Savings Card. Eligible cash-paying patients and commercially insured patients/RX not covered may pay $75 per 30g prescription; offer valid 12 times per calendar year; for additional information contact the program at 855-280-0543. Applies to: Tri-Luma Number of uses: 12 times within calendar yearTri-Luma Cream is used for Lightens light brown color patches on skin, Age spots, Skin discolorations associated with pregnancy, Rough patches and tiny bumps on skin, Skin trauma, and other conditions. Tri-Luma Cream may also be used for purposes not listed in this medication guide. Tri-Luma Cream contains Fluocinolone Acetonide.Which patents cover Tri-luma, and when can generic versions of Tri-luma launch? Tri-luma is a drug marketed by Galderma Labs Lp and is included in one NDA. There are two patents protecting this drug. This drug has twenty-nine patent family members in eighteen countries. The generic ingredient in TRI-LUMA is fluocinolone acetonide; hydroquinone ...It works by decreasing the amount of melanin, a pigment your body makes that gives your skin color. This reduces the appearance of dark spots. Sun prevention measures, including sunscreen, are often combined with this medication. It is a combination of a topical steroid, a skin-lightening agent, and a retinoid. Aug 1, 2023 · Tri-Luma; Descriptions. Fluocinolone, hydroquinone, and tretinoin topical is a combination of medicines used to treat moderate to severe melasma (skin discoloration) of the face. Melasma usually happens with hormone changes in women. Feb 24, 2021 · Kem trị nám Tri Luma của Ấn Độ giá cả sẽ dao động trong khoảng 400K – 600K tùy vào từng nơi bán và từng thời điểm bán. Nhìn chung kem trị nám Tri Luma có xuất xứ từ Mỹ thường có giá cao hơn rất nhiều, gấp 2 – 3 lần so với kem trị nám Tri Luma đến từ Ấn Độ. • TRI-LUMA Cream, a combination drug product containing corticosteroid, retinoid, and bleaching agent, is NOT indicated for the maintenance treatment of melasma. After achieving control with TRI-LUMA Cream, some patients may be managed with other treatments instead of triple therapy with TRI-LUMA Cream.Clinically Proven Treatment Can Help More than 7 Million Suffering from Melasma in the U.S. Fort Worth, Texas (February 12, 2013) - Galderma Laboratories, L.P.’s Tri-Luma® (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) Cream, the only FDA-approved triple combination topical product indicated for the short-term (up to 8 weeks) treatment of moderate to severe melasma of the ...Tri-Luma Coupons, Prices, and Savings Card. This combination medication is used to treat melasma on the face. Learn more about fluocinolone-hydroquinone-tretinoin topical . 1 . This is a brand name drug and a generic may be available. The average cost for 1 Tube Of Cream, 30gm of 0.01-4-0.05% each, is $278.99. After stopping Tri-Luma, some of the color change may come back. Some weather conditions may irritate the skin. Talk with the doctor. Use of other skin products while using Tri-Luma may cause more irritation. Talk with your doctor before you use other drugs or products on your skin. Practice good skin care and avoid the sun.Aug 31, 2023 · Which patents cover Tri-luma, and when can generic versions of Tri-luma launch? Tri-luma is a drug marketed by Galderma Labs Lp and is included in one NDA. There are two patents protecting this drug. This drug has twenty-nine patent family members in eighteen countries. The generic ingredient in TRI-LUMA is fluocinolone acetonide; hydroquinone ... Tri Luma cream combines three active ingredients: Fluocinolone acetonide is a corticosteroid that helps reduce inflammation and irritation in the skin 4. Hydroquinone is a first-line treatment used for depigmentation or skin lightening agent, it works by inhibiting the production of melanin, the pigment responsible for skin color. Hydroquinone ...Tri-Luma крем предназначен для топической терапии темных пятен, которые связанные с меланодермией лица, купить по низкой цене в интернет-магазине Great Pharma TRI-LUMA MR debe aplicarse una vez al día por la noche, por lo menos 30 minutos antes de acostarse. Lave el rostro y el cuello con un dermolimpiador suave. Enjuague abundantemente y seque la piel. Aplique una delgada película del producto en las áreas hiperpigmentadas incluyendo aproximadamente ½ cm de piel normal alrededor de cada lesión.
1. 7. 7 comments. C_Chrono • 3 yr. ago. I started tretinoin first. It helped with acne scars but did not help with sun spots. So after more than a year of almost daily use without buffering, I opted for Tri-Luma. I followed the instructions faithfully and used it for 8 weeks only. I was already using 0.05 tretinoin for months so the ... . Woman
TRI-LUMA Cream is a combination of fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) that is indicated for the short-term treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens.Triluma Cream quantity. Triluma Cream is a product manufactured by Galderma. Is a well-established item for treating the condition Melasma. Triluma is Tri-luma generic cream. The active ingredients are Hydroquinone 4%, Tretinoin 0.05%, and Fluocinolone acetonide 0.01% help in cleaning and complete removal of all kinds of marks such as pregnancy ...A dermatologist stated (see link) that "you'll know Tri-luma expired when it changes the color". New Triluma is light yellow. To WHAT does the color change TO when the product expires? For example, my Tri-luma is 4 years past expiry date and the color is still as if bought yesterday (light yellow). Given, I've stored it in the fridge or away ...Feb 12, 2013 · Clinically Proven Treatment Can Help More than 7 Million Suffering from Melasma in the U.S. Fort Worth, Texas (February 12, 2013) - Galderma Laboratories, L.P.’s Tri-Luma® (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) Cream, the only FDA-approved triple combination topical product indicated for the short-term (up to 8 weeks) treatment of moderate to severe melasma of the ... Apply just enough cream to cover the discolored spots and about one-half inch of the normal skin surrounding the affected area. Lightly rub onto your skin. The medicine should become invisible almost at once. If you can still see the medicine, you are using too much. Use your medicine at regular intervals. • TRI-LUMA Cream, a combination drug product containing corticosteroid, retinoid, and bleaching agent, is NOT indicated for the maintenance treatment of melasma. After achieving control with TRI-LUMA Cream, some patients may be managed with other treatments instead of triple therapy with TRI-LUMA Cream.Compare prices and print coupons for Tri-Luma (Fluocinolone, Hydroquinone, and Tretinoin) and other drugs at CVS, Walgreens, and other pharmacies. Prices start at $216.43• TRI-LUMA Cream, a combination drug product containing corticosteroid, retinoid, and bleaching agent, is NOT indicated for the maintenance treatment of melasma. After achieving control with TRI-LUMA Cream, some patients may be managed with other treatments instead of triple therapy with TRI-LUMA Cream.TRI-LUMA Cream is contraindicated in individuals with a history of hypersensitivity, allergy, or intolerance to this product or any of its components. WARNINGS TRI-LUMA Cream contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening asthmatic episodes in susceptible people. Some dosage forms listed on this page may not apply to the brand name Tri-Luma. Summary. Common side effects of Tri-Luma include: burning sensation, desquamation, pruritus, erythema of skin, and xeroderma. Continue reading for a comprehensive list of adverse effects.Tri luma cream is a prescription-based combination formulation for treating face melasma. The medicinal property of Triluma prevents skin redness, itchiness and swelling. Melasma commonly appears as a dark, patchy spot on the skin (especially on the forehead, cheeks, and chin area).About the CARE Connect Card. For a patient with a skin condition requiring prescription treatments, the promises of some discount programs are either too complicated, temporary or more hassle than they are worth. Through Galderma CAREConnect, eligible patients can get remarkable savings, paying as little as $0 on some Galderma prescription ...Let’ s have a look below on the active ingredients of Tri-luma cream and their mode of action: Fluocinolone Acetonide 0.01% - this ingredient helps and reduces skin inflammation. Hydroquinone 4% - this agent discourages the pigmentation process; Tretinoin 0.05% - contains vitamin A that increases and exfoliates the complete skin cells. TRI-LUMA Cream is a combination of fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) that is indicated for the short-term treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens..